Tuesday, January 23, 2024

2 jabs annually to control cholesterol.

There is now some help at hand to those struggling to bring their cholesterol under control as a breakthrough cholesterol-lowering treatment that promises to drastically reduce LDL-C (Low-density lipoprotein cholesterol) in the blood or 'bad' cholesterol has been launched in India.

Inclisiran, which has got approval from the Drug Controller General of India (DCGI), has been termed as a futuristic drug and is only required to be taken twice a year. However, it costs around Rs.1.3 lakhs per dose.

Important information

* Inclisiran is a cholesterol-lowering drug that reduces levels of LDL cholesterol in the blood
* It is a gene-silencing drug as that silences the gene PCSK9, which in turn boosts the liver's ability to
   remove harmful cholesterol from the blood
* After an initial dose, the drug is given again after three months and then twice a year
* Each 284 mg dose is administered using a single pre-filled syringe

Recommended for

* Those whose cholesterol has not gone down despite being on statin
* Have recurrent or family history of cardiovascular events
* Experience too many statin side effects and are unable to take them

Side effects

* Local injection site reactions
* Some muscle-associated symptoms
* Symptoms like a common cold with inflammation in the nasal passages
* Headaches


Tailpiece.

Got up at a 10' to 6, the chores and was ready by a half past 9.

Subin came by and cleaned up the overhead water tank.

Riby and Ajish came by to finalise repainting The Quarterdeck.

The evening chores. 

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